| 1 | TM | STUDYID | Study Identifier | Char | | Identifier | Req | Unique identifier for a study. |
| 2 | TM | DOMAIN | Domain Abbreviation | Char | | Identifier | Req | Two-character abbreviation for the domain, which must be TM. |
| 3 | TM | MIDSTYPE | Disease Milestone Type | Char | | Topic | Req | The type of disease milestone. Example: "HYPOGLYCEMIC EVENT". |
| 4 | TM | TMDEF | Disease Milestone Definition | Char | | Variable Qualifier | Req | Definition of the disease milestone. |
| 5 | TM | TMRPT | Disease Milestone Repetition Indicator | Char | C66742 | Record Qualifier | Req | Indicates whether this is a disease milestone that can occur only once ("N") or a type of disease milestone that can occur multiple times ("Y"). |